CJC-1295 w/o DAC_RUO 5mg
Price range: $115.00 through $999.00
CJC-1295 without DAC is a modified analog of Growth Hormone-Releasing Hormone (GHRH 1-29) with four amino acid substitutions (at positions 2, 8, 15, and 27) designed to enhance stability against enzymatic degradation compared to native GHRH. Unlike the DAC version, it lacks the Drug Affinity Complex modification, resulting in a shorter plasma half-life and a more pulsatile GH release profile in laboratory models. It is commonly studied in cell-based assays, pituitary cell cultures, and animal models for its effects on growth hormone secretion, the GH/IGF-1 axis, endocrine signaling, and related metabolic processes.
The product is provided as a sterile lyophilized powder, typically appearing as a white to off-white solid in a sealed vial.
Product Overview
CJC-1295 without DAC is a modified analog of Growth Hormone-Releasing Hormone (GHRH 1-29) with four amino acid substitutions (at positions 2, 8, 15, and 27) designed to enhance stability against enzymatic degradation compared to native GHRH. Unlike the DAC version, it lacks the Drug Affinity Complex modification, resulting in a shorter plasma half-life and a more pulsatile GH release profile in laboratory models. It is commonly studied in cell-based assays, pituitary cell cultures, and animal models for its effects on growth hormone secretion, the GH/IGF-1 axis, endocrine signaling, and related metabolic processes.
The product is provided as a sterile lyophilized powder, typically appearing as a white to off-white solid in a sealed vial.
Specifications (Typical)
• Active Ingredient: CJC-1295 without DAC – 10 mg per vial
• Synonyms: Modified GRF (1-29), tetrasubstituted GRF (1-29), CJC-1295 no DAC
• CAS Number: 446036-97-1 (or 863288-34-0 in some references)
• Molecular Formula: C₁₅₂H₂₅₂N₄₄O₄₂
• Molecular Weight: Approximately 3367.9 g/mol
• Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH₂
• Purity: ≥98–99% (verified by HPLC and other analytical methods; Certificate of Analysis typically available)
• Form: Lyophilized powder in a sterile glass vial
• Solubility: Soluble in bacteriostatic water or sterile aqueous buffers for reconstitution in laboratory settings
• Storage:
• Lyophilized: Store at -20°C or lower, protected from light and moisture
• Reconstituted: Refrigerate at 2–8°C and use promptly to maintain stability
• Shelf Life: Typically 24 months when stored properly in lyophilized form
Intended Use Statement (RUO Compliant)
This product is strictly for laboratory research use only (RUO). It is not intended, approved, or suitable for human consumption, animal use, clinical applications, diagnostic procedures, or any form of medical treatment. All handling, experimentation, and data interpretation must comply with applicable institutional, local, and federal regulations governing research chemicals. Any claims regarding potential biological effects (such as stimulation of pulsatile GH secretion) are for research context only and have not been evaluated by regulatory authorities such as the FDA for safety or efficacy in humans or animals.
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