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FDA Disclaimer: The content and products mentioned on this website have not been evaluated by the U.S. Food and Drug Administration (FDA). These products are not intended to diagnose, treat, cure, or prevent any disease. All products are sold exclusively for research, laboratory, or analytical purposes and are not intended for human consumption. The information provided is strictly for informational purposes only. All products are sold for research, laboratory, or analytical purposes only, and are not for human consumption. PRODUCTS ARE NOT FOR RESALE.

Retatrutide RUO 40mg

Price range: $220.00 through $1,199.00

Retatrutide RUO 40mg from Profound Peptides is the largest single-vial format available for this compound. Each vial contains 49.66mg net peptide, independently verified at 99.689% purity by Freedom Diagnostics (COA: 2603130116, Lot: RET40-2162026). It is the format labs reach for when a study runs long, spans multiple treatment arms, or requires consistent peptide stock across a full research cycle without reordering mid-protocol. Freedom Diagnostics testing is publicly searchable at FreedomDiagnosticsTesting.com. For in vitro laboratory and scientific research use only. Not for human consumption.
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SKU: PP-401 Category:

Retatrutide RUO 40mg — Full Product Specifications

Specification Detail
Also Known As
CAS Number 2381089-83-2
Molecular Formula C221H342N46O68
Molecular Weight ~4,731 Da
Sequence Length 39 amino acids
Vial Size 40mg per vial
Form White lyophilized powder
Purity — this batch 99.689% — Freedom Diagnostics verified
Net Peptide Content 49.66mg confirmed
Testing Method HPLC + UV Detection + Mass Spectrometry (LCMS/MS)
Lot Number RET40-2162026
COA Accession 2603130116 — publicly verifiable at FreedomDiagnosticsTesting.com
Half-life ~144 hours (~6 days) in relevant research models
Long-term storage -20°C, sealed vial, up to 24 months
Short-term storage 2 to 8°C, up to 28 to 30 days reconstituted
Intended Use In vitro laboratory research only — not for human use

Certificate of Analysis — Freedom Diagnostics

Each vial ships with access to a batch-specific COA from Freedom Diagnostics, a US-owned independent testing laboratory. The current 40mg batch result is publicly searchable using the accession number below.

COA Field Detail
PURITY RESULT 99.689%
TESTING LAB Freedom Diagnostics (USA)
LOT NUMBER RET40-2162026
COA / ACCESSION 2603130116
TESTING METHOD HPLC + Mass Spectrometry (LCMS/MS)
NET PEPTIDE CONTENT 49.66mg confirmed
RECEIVED DATE 03/13/2026
REPORT DATE 03/15/2026
PRINCIPAL CHEMIST Alex Johnson

 

CTA:

Download COA PDF

Retatrutide RUO 40mg is the format suited to labs that plan their peptide supply before a study starts, not around it. A single 40mg vial reconstituted at 4mL gives a working concentration of 10mg/mL and approximately 4.96mL of usable solution. That is enough volume to support multiple independent treatment arms, run dosing titration curves, maintain a control group, and still have working stock remaining for satellite assays or protocol extensions — without touching a second vial.
Research groups that use this format tend to be running MASLD or hepatic fat studies requiring extended treatment windows, multi-receptor comparative studies where Retatrutide serves as the triple agonist reference compound, institutional preclinical programs tracking weight and metabolic markers across full study cycles, oncology models where consistent compound availability matters for tumor progression timelines, or research programs where batch-to-batch variability is a risk factor. One vial, one lot number, one COA. That consistency matters when you need your data to be reproducible.

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Who should order the 40mg format over the 10mg or 20mg?

Labs running extended protocols, multi-arm preclinical studies, or programs that cannot afford a supply gap mid-study. The 40mg format reduces reorder frequency, eliminates inter-batch variability risk, and lowers cost per milligram compared to smaller vials. If your study runs longer than 4 weeks or requires more than two treatment groups, the 40mg is worth the calculation.

What purity is this batch of Retatrutide 40mg?

99.689%, independently verified by Freedom Diagnostics via HPLC with UV Detection and Mass Spectrometry (LCMS/MS). COA accession 2603130116, net peptide content confirmed at 49.66mg. Searchable directly at FreedomDiagnosticsTesting.com using the accession number — no contact with Profound Peptides needed.

How much working solution can I get from a 40mg vial?

At 4mL of bacteriostatic water, you get a 10mg/mL working concentration and approximately 4.96mL of usable solution based on confirmed net peptide content of 49.66mg. For studies requiring lower concentrations, use more solvent volume — just adjust your volume calculations accordingly. Some researchers prefer 2mL for a 20mg/mL stock that they then dilute for specific assay concentrations.

How do I handle aliquoting for a 40mg vial?

For any protocol that spans more than a few weeks, divide the reconstituted solution into single-use volumes before storing. Label each aliquot with date, concentration, and study ID. Store at 2 to 8°C and use within 28 to 30 days. Do not refreeze reconstituted solution. For long-duration studies, consider keeping the remainder of the lyophilized powder at -20°C and reconstituting in smaller batches as needed.

Does a larger vial mean lower purity or different compound quality?

No. The compound, testing methodology, and purity standard are identical across all three Retatrutide vial sizes (10mg, 20mg, 40mg). The 40mg format uses the same Freedom Diagnostics verification process. Each batch has its own independent COA. Lot RET40-2162026 tested at 99.689%.

Is the 40mg format suitable for in vitro cell studies or only animal models?

Both. The 40mg format works for in vitro receptor binding assays, cellular signaling studies, and animal model protocols. The larger stock is particularly useful in animal studies where treatment duration runs 24 to 48 weeks — a common timeline in the published Retatrutide Phase 2 literature. For short in vitro assays, the 10mg or 20mg format is often sufficient.

What is the cost advantage of the 40mg over smaller vials?

The 40mg vial at $220 works out to $5.50 per mg. The 10mg vial at $85 is $8.50 per mg. For labs purchasing at scale, the 40mg format represents a roughly 35% cost reduction per milligram while maintaining identical purity standards and third-party verification.

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