IGF-1LR3_RUO 1mg

IGF-1 LR3 (Long Arg³ Insulin-like Growth Factor-1) is a recombinant, synthetic analog of human IGF-1, modified for extended half-life and enhanced biological activity in controlled laboratory environments. This 83-amino-acid peptide incorporates an arginine substitution at position 3 (Arg³) and an additional 13-amino-acid extension at the N-terminus. These structural changes significantly reduce affinity for insulin-like growth factor binding proteins (IGFBPs), prolong the compound’s stability (reported half-life of approximately 20–30 hours in relevant models), and increase potency in receptor-mediated signaling pathways compared to native IGF-1. IGF-1 LR3 is supplied as high-purity lyophilized powder (>98% purity, verified by HPLC and mass spectrometry) and is intended exclusively for in vitro research applications. It is commonly utilized in laboratory studies investigating cellular proliferation, differentiation, apoptosis regulation, tissue regeneration mechanisms, metabolic signaling (e.g., via IGF-1 receptor pathways), and related growth factor dynamics in cell culture, animal tissue models, or biochemical assays.